Back to home page

Conservative treatment for cattle DA - does Buscopan make a difference?

Clinical Scenario

You attend a call to examine a freshly calved cow that is off its feed. You diagnose a right displaced abomasum (RDA). The cow is cardiovascularly stable and you suspect the abomasum is dilated but that there is no torsion or volvulus. You offer to carry out a laparotomy and surgical correction but the farmer declines as the cow is "not that sick". You advise monitoring the cow and calling back if she deteriorates. On returning to the practice one of your colleagues suggests that you could give the cow Buscopan compositum to increase the chance of recovery. You wonder if there is any evidence to support this for displaced abomasa generally, particularly given you are aware the product is not licensed for use in cows producing milk for human consumption...

3-Part Question (PICO)

In [cows with displaced abomasa] does treatment with [Buscopan compositum versus no treatment] result in [better rates of cure]?

Search Strategy and Summary of Evidence

Search Strategy

MEDLINE(R) In-Process & Other Non-Indexed Citations and MEDLINE(R) 1946 to Present using the OVID interface

(cow.mp. OR cows.mp. OR cattle.mp. OR bovine.mp. OR bovines.mp. OR bos.mp. OR exp cattle/)

AND

(abomasal displacement.mp. OR DA.mp. OR DAs.mp. OR abomasum.mp. OR abomasums.mp. OR abomasa.mp. OR exp Abomasum/)

AND

(buscopan.mp. OR buscopan compositum.mp. OR butylscopolamine bromide.mp. OR hyoscine.mp. OR hyoscine butylbromide.mp. OR Hyoscine-N-Butylbromide.mp. OR exp Butylscopolammonium Bromide/)

CAB Abstracts 1910 to Present using the OVID interface

(cow.mp. OR cows.mp. OR cattle.mp. OR bovine.mp. OR bovines.mp. OR bos.mp. OR exp cows/ OR exp cattle/)

AND

(abomasal displacement.mp. OR DA.mp. OR DAs.mp. OR abomasum.mp. OR abomasums.mp. OR abomasa.mp. OR exp abomasum/)

AND

(buscopan.mp. OR buscopan compositum.mp. OR butylscopolamine bromide.mp. OR hyoscine.mp. OR hyoscine butylbromide.mp. OR Hyoscine-N-Butylbromide.mp.)

Search Outcome

MEDLINE

  • 1 papers found in MEDLINE search
  • 1 papers excluded as they don't meet the PICO question
  • 0 papers excluded as they are in a foreign language
  • 0 papers excluded as they are review articles/in vitro research/conference proceedings
  • 0 total relevant papers from MEDLINE

CAB Abstracts

  • 5 papers found in CAB search
  • 4 papers excluded as they don't meet the PICO question
  • 0 papers excluded as they are in a foreign language
  • 1 papers excluded as they are review articles/in vitro research/conference proceedings
  • 0 total relevant papers from CAB

Total relevant papers

0 relevant papers from both MEDLINE and CAB Abstracts

Comments

No citations have been included in this BET as none of the papers found directly compared the interventions of interest to each other (i.e. they did not answer the PICO question) or were non-peer reviewed articles. Therefore, the table of evidence below has been left blank. 

Summary of Evidence

No Summary of Evidence yet.

Comments

None of the published articles which were found directly compared the interventions of interest in this BET.  It is worth noting that Buscopan compositum is not currently licenced for use in DA in cows in the UK and the product datasheet specifically states that it is not to be used in cows producing milk for human consumption.

Narrative reviews and expert opinion pieces, along with other sources such as textbooks and online resources (e.g. Vetstream or The Merck Veterinary Manual), can be used when deciding which treatment to employ. However, an awareness of the strengths and limitations of all of these evidence sources in relation to decision-making is important.

There is a need for further research to directly compare success rates and possible side effects of the treatments for medical/conservative approaches to displaced abomasa, in order to improve the strength of the evidence base in this area.   Assessing the success of surgical approaches for some types of displaced abomasa have been the focus of previous BETs.

Bottom line

At the present time, there is no comparative peer-reviewed evidence that focuses on the medical management of displaced abomasa involving Buscopan compositum.  Therefore, choice of treatment should be based on the veterinarian's preferred approach or individual practice guidelines.

Disclaimer

The BETs on this website are a summary of the evidence found on a topic and are not clinical guidelines. It is the responsibility of the individual veterinary surgeon to ensure appropriate decisions are made based on the specific circumstances of patients under their care, taking into account other factors such as local licensing regulations. Read small print

References

About this BET

First author:
Marnie Brennan
Second author:
John Remnant
Institution:

University of Nottingham

Search last performed:
2017-04-28 11:28:31
Original publication date:
2017-04-28 11:28:31
Last updated:
2017-04-28 11:28:31
About BETs?

A BET is a simple method of searching for and appraising evidence around a very specific clinical situation.

Read more …

Using BETs?

BETs don’t tell you what to do, they tell you about the evidence on a certain topic.

Read more …

Not a Vet?

This website has been designed to help vets use the best, most relevant, up to date science when they make decisions about their patients.

Read more …