Back to home page

Oxytetracycline spray following disbudding in calves

Clinical Scenario

You are called to a farm owned by Mr Clarke, a regular client of the practice, to perform disbudding on a group of 12 calves. You carry out cornual nerve blocks on the calves, before using a hot iron to cauterise the horn buds and surrounding skin. You follow this procedure by spraying the wounds with oxytetracycline spray. As you perform the procedure Mr Clarke chats to you about recent news coverage around antimicrobial resistance, which gets you wondering about whether using oxytetracycline spray following disbudding is neccessary. You wonder if there is any evidence to suggest that the use of oxytetracycline spray reduces the rate of infection following disbudding...

3-Part Question (PICO)

In [calves undergoing disbudding] does [the administration of oxytetracycline spray compared to no oxytetracycline spray] post procedure reduce [incidence of bacterial infection]?

Search Strategy and Summary of Evidence

Search Strategy

MEDLINE(R) In-Process & Other Non-Indexed Citations and MEDLINE(R) 1946 to Present using the OVID interface

(calf.mp. OR calves.mp. OR bovine$.mp. OR cattle.mp. OR young stock.mp. OR youngstock.mp. OR bos.mp. OR cow$.mp. OR exp Cattle/)

AND

(disbud.mp. OR disbudding.mp. OR disbudded.mp. OR de horn.mp. OR de horning.mp. OR de horned.mp. OR dehorn.mp. OR dehorning.mp. OR dehorned.mp. OR horn removal$.mp. OR horn removing.mp. OR bud removal$.mp. OR bud removing.mp.)

AND

(oxytetracycline.mp. OR oxytetracyclines.mp. OR tetracycline.mp. OR tetracyclines.mp. OR oxytet.mp. OR OTC.mp. OR terramycin.mp. OR topical antibiotic.mp. OR topical antibiotics.mp. OR antibiotic spray.mp. OR blue spray.mp. OR antibiotic.mp. OR antibiotics.mp. OR antimicrobial.mp. OR antimicrobials.mp. OR antibacterial.mp. OR antibacterials.mp. OR anti-bacterial.mp. OR anti-bacterials.mp. OR exp Oxytetracycline/ OR exp Tetracyclines/ OR exp Anti-Bacterial Agents/)

CAB Abstracts 1910 to Present using the OVID interface

(calf.mp. OR calves.mp. OR bovine$.mp. OR cattle.mp. OR young stock.mp. OR youngstock.mp. OR bos.mp. OR cow$.mp. OR exp calves/ OR exp cows/ OR exp cattle/)

AND

(disbud.mp. OR disbudding.mp. OR disbudded.mp. OR de horn.mp. OR de horning.mp. OR de horned.mp. OR dehorn.mp. OR dehorning.mp. OR dehorned.mp. OR horn removal$.mp. OR horn removing.mp. OR bud removal$.mp. OR bud removing.mp. OR exp disbudding/ OR exp dehorning/)

AND

(oxytetracycline.mp. OR oxytetracyclines.mp. OR tetracycline.mp. OR tetracyclines.mp. OR oxytet.mp. OR OTC.mp. OR terramycin.mp. OR topical antibiotic.mp. OR topical antibiotics.mp. OR antibiotic spray.mp. OR blue spray.mp. OR antibiotic.mp. OR antibiotics.mp. OR antimicrobial.mp. OR antimicrobials.mp. OR antibacterial.mp. OR antibacterials.mp. OR anti-bacterial.mp. OR anti-bacterials.mp. OR exp oxytetracycline/ OR exp tetracyclines/ OR exp antibiotics/ OR exp antibacterial agents/)

Search Outcome

MEDLINE

  • 5 papers found in MEDLINE search
  • 5 papers excluded as they don't meet the PICO question
  • 0 papers excluded as they are in a foreign language
  • 0 papers excluded as they are review articles/in vitro research/conference proceedings
  • 0 total relevant papers from MEDLINE

CAB Abstracts

  • 25 papers found in CAB search
  • 25 papers excluded as they don't meet the PICO question
  • 0 papers excluded as they are in a foreign language
  • 0 papers excluded as they are review articles/in vitro research/conference proceedings
  • 0 total relevant papers from CAB

Total relevant papers

0 relevant papers from both MEDLINE and CAB Abstracts

Comments

No citations have been included in this BET as no papers were found looking at the use of oxytetracycline spray following disbudding (ie. no peer-reviewed evidence to answer the PICO question). Therefore, the table of evidence below has been left blank.

Summary of Evidence

No Summary of Evidence yet.

Comments

No relevant papers were found during the searches despite disbudding being a commonly performed procedure in farm animal practice. 

Antimicrobial use, with particular focus on the development of antimicrobial resistance, has been the subject of much recent debate. The impact of topical antimicrobial treatments on the development of antimicrobial resistance is unknown.  As part of any therapeutic plan involving antimicrobials, including those delivered topically, the possible development of resistance should be considered.

Bottom line

At the present time there is no peer-reviewed evidence examining the use of topical oxytetracycline spray following disbudding in calves and its impact on post procedural infection rates. Therefore, when deciding whether to use this treatment, practitioners should take into account other factors such as their own clinical experience and product licensing recommendations.

Disclaimer

The BETs on this website are a summary of the evidence found on a topic and are not clinical guidelines. It is the responsibility of the individual veterinary surgeon to ensure appropriate decisions are made based on the specific circumstances of patients under their care, taking into account other factors such as local licensing regulations. Read small print

References

About this BET

First author:
Natalie Robinson
Second author:
Marnie Brennan
Institution:

CEVM, University of Nottingham

Search last performed:
2017-11-27 16:54:23
Original publication date:
2017-12-01 16:54:23
Last updated:
2017-12-01 16:54:23
About BETs?

A BET is a simple method of searching for and appraising evidence around a very specific clinical situation.

Read more …

Using BETs?

BETs don’t tell you what to do, they tell you about the evidence on a certain topic.

Read more …

Not a Vet?

This website has been designed to help vets use the best, most relevant, up to date science when they make decisions about their patients.

Read more …